Focusing on the centromere—the part of each chromosome that interacts with spindle microtubules to direct segregation in mitosis or meiosis—we found that the structure’s size determines the direction ...

View Full Profile. Learn about our Editorial Policies. Centromeres are important elements of chromosomes that are responsible for the proper separation of chromosomes during cell division. This ...

Without centromeres, cells cannot divide properly and the overall process of mitosis fails. Why are these small chromosomal regions so essential to such a major cellular process? With a few ...

If centromeres are missing or in the wrong place, then the genetic information is not shared correctly between the dividing ...

A genomic study of human and selected nonhuman primate centromeres has revealed their unimaginable diversity and speed of ...

Dicentric chromosomes with well–separated centromeres are functionally monocentric, stabilized by the poorly understood phenomenon of centromere inactivation. We show here that dicentric X ...