Transmembrane proteins involve various physiological functions, including protein ligation, recognition, transport, anchoring, and transduction. Several diseases are connected with abnormalities ...

Many of these proteins are embedded into the membrane and stick out on both sides; these are called transmembrane proteins. The portions of these proteins that are nested amid the hydrocarbon ...

Anchor proteins can physically link intracellular structures with extracellular structures. Protein surfaces are designed for interaction. Learn how proteins can bind and release other molecules ...

A team of researchers has identified a mechanism that regulates the production of two different proteins from the same gene.

The FDA expanded the approval of Pluvicto (lutetium Lu 177 vipivotide tetraxetan) to include patients with PSMA-positive mCRPC who have been treated with ARPI therapy and are considered appropriate to ...

Inherited retinal degeneration (IRD) encompasses various disorders characterized by progressive loss of retinal photoreceptor cells, ultimately ...

VLPs can display membrane proteins in their full natural conformation on the surface of virus-like particles, resulting in full-length transmembrane proteins suitable for immunization and antibody ...

Recent studies have shown that CD44, a transmembrane protein that plays an essential role in transducing extracellular stimuli into intracellular signaling cascades, contributes to metabolic ...

Ion channel proteins are concerned with inorganic ion transport, which is crucial for maintaining cellular homeostasis and metabolism. Their structural and functional abnormalities are related to ...

As CDH17 is an abundantly expressed and rapidly internalizing transmembrane protein on GI cancer cells, CDH17 is ideally suited for an ADC-mediated drug delivery approach. SOT109 is a fully human ...