In eukaryotes, termination of transcription occurs by different processes, depending upon the exact polymerase utilized. For pol I genes, transcription is stopped using a termination factor ...

Here they show that SSUP-72/PINN-1 regulates Pol II 3′ pausing and transcription termination in C. elegans. Its loss bypasses the need for CDK-12 during development, uncovering a novel mechanism ...

The process of transcription elongation by RNA polymerase ... SPT5 is lost and forces Pol II to enter a "noncanonical early termination pathway," in which Pol II is ultimately degraded.

Transcription is a tightly regulated event crucial for gene expression. This process can be broadly divided into three distinct stages: initiation, elongation, and termination. Transcription ...