Overall, however, the net clinical benefit—based on an endpoint incorporating all stroke and systemic embolism, MI, cardiovascular death, and major bleeding—tends to lean toward giving the DOAC versus ...

Future Cardiol. 2012;8(6):847-861. The benefits of surgery to prevent embolism are therefore greatest at an early stage, deferral of surgery for 2–3 weeks for this indication alone is of little ...