Currently, Azure File Sync just works with Windows Server 2016 and Windows Server 2012 R2, but Microsoft could support earlier server products if it gets customer requests to that effect.

Azure File Sync just supports New Technology File System (NTFS) volumes. There's no support for the Resilient File System (ReFS), File Allocation Table (FAT) or FAT32 file systems. Organizations must ...

With Windows 365 cloud PCs planned to be just another virtual desktop in Windows 11, having a file system like Azure Files that’s shared between your PC and those cloud PCs is going to be essential.