Because pituitary corticotroph adenomas express somatostatin receptors, somatostatin analogues have been investigated as a potential targeted therapy for the treatment of Cushing's disease.

In mouse models of type 1 diabetes, the secretion of glucagon for the counter-regulation of blood sugar levels is restored ...

The healthy cells receive a low dose or no radiation. Special scans can check whether your NET has these receptors. If your NET has somatostatin receptors, doctors can use these receptors to target ...

First, the researchers assessed how well Consomatin G1 bound to all five SSTR receptors, by synthesizing the previously identified peptide (Consomatin pG1). This peptide, isolated from cone snail ...

Peptide receptor radiotherapy is a new treatment option for patients with high tumor content of somatostatin type 2 receptors and will be further developed in the future.

"Human somatostatin binds to five different membrane receptors to elicit a myriad of physiological actions," said Ho Yan ...

SST receptors (SSTRs) constitute a superfamily ... Such deals may include upfront development fees and downstream royalties. “Our somatostatin-based targeted radiotherapy represents a potential ...

Ariceum Therapeutics GmbH’s radiopharmaceutical 225Ac-SSO110 ([225Ac]satoreotide tetraxetran) has been awarded orphan drug designation by the FDA for the treatment of small-cell lung cancer (SCLC).

G-protein coupled receptors regulate hormone secretions ... including cells that secrete the hormones somatostatin, ghrelin, and pancreatic polypeptide Y. They have also discovered that the ...

Supplemental BLA accepted for review Paltusotine (Crinetics Pharmaceuticals) Somatostatin receptor ... N-methyl-D-aspartate receptor antagonist, sigma-1 agonist, and aminoketone CYP2D6 inhibitor ...