Symptoms: FOP causes the body's muscle and connective tissue to be gradually replaced with bone tissue. This essentially forms a second skeleton that impedes the person's movement. One of the ...

essentially causing the body to grow a second skeleton. It is an extremely rare disease that is estimated to affect around one in one million people. FOP is caused by a mutation in a gene known as ...

The genetic twist that leads to FOP, is relevant to every condition that affects the formation of bone and every condition that affects the formation of the skeleton,' said Dr. Frederick Kaplan ...

The symptoms can easily be mistaken for those of other diseases; FOP is ultra-rare, affecting only one in 1.4 million people 1, so many health-care professionals (HCPs) are unaware of it.