Previously on metformin alone: initially 100mg daily of sitagliptin plus metformin dose. Previously on metformin 850mg twice daily or 1000mg twice daily: start with two 50mg/1000mg tablets (taken ...

The study group consisted of stratum 1 (glimepiride alone, n = 212) and stratum 2 (glimepiride plus metformin, n = 229). Patients in each stratum were randomized to sitagliptin 100 mg once daily ...