In the one completed outcomes trial to date – the Simvastatin and Ezetimibe in Aortic Stenosis (SEAS) trial – in aortic stenosis patients, ezetimibe plus statin therapy did not reduce the ...

Your doctor can adjust your dosage or prescribe a different statin for you. "If statins aren't a good fit, options like ezetimibe or PCSK9 inhibitors (like evolocumab or alirocumab) can be great ...

In addition to niacin and ezetimibe, 75% of these patients were taking a statin. After the addition of ezetimibe, the mean reduction in LDL cholesterol levels was 25%, but there was no change in ...

Compared with a statin alone, the addition of Praluent cost $308 000 per quality-adjusted life year (QALY) gained. But the addition of ezetimibe cost $81 000 per QALY compared with a statin alone.

It requires great deal of optimism to draw therapy-relevant conclusions from the results of IMPROVE-IT, the key trial addressing a potential benefit of the addition of ezetimibe to simvastatin ...

Ezetimibe is a nonstatin low-density lipoprotein cholesterol-lowering small molecule drug. Ezetimibe is the only currently FDA-approved approved member of the of intestinal cholesterol reuptake ...

and Vytorin (ezetimibe and simvastatin) and the expiration of some key patents. Merck's new biotech division will take advantage of its GlycoFi technology, purchased in 2006. This glyco ...

In the one completed outcomes trial to date – the Simvastatin and Ezetimibe in Aortic Stenosis (SEAS) trial – in aortic stenosis patients, ezetimibe plus statin therapy did not reduce the ...