Title: QTX3544, a potent and selective G12V-preferring KRAS inhibitor, synergizes with EGFR inhibitors for enhanced anti-tumor activity Date and Time: Wednesday, April 30, 2025; 9:00 AM - 12:00 PM ...
A growing body of work suggests that cell metabolism — the chemical reactions that provide energy and building materials — ...
In fruit flies, the signaling cascade is initiated by maternally provided transcripts that are present in eggs at the time of fertilization. While transcripts like caudal (cad) and hunchback (hb ...
Fruit flies with genetic mutations that severely reduce sleep show enhanced performance in olfactory memory tasks, ...
The binding of adrenaline to an adrenergic receptor initiates a cascade of reactions inside the cell. The signal transduction cascade begins when adenylyl cyclase, a membrane- bound enzyme ...
Fruit fly mutants that have severe sleep deficits perform better at olfactory learning and memory tasks, according to a study published in the open-access journal PLOS Biology by Sheng Huang and ...
Upon aversive stimulus (electric foot shock), acetylcholine activates PAK kinase through the M1R-PKC cascade to facilitate synaptic plasticity. It also enhances PKC-mediated KCNQ2 phosphorylation ...
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