The ERBB receptors are a group of receptor tyrosine kinases (RTKs) involved in key cellular functions including cell growth and survival. What are the activation mechanisms particular to ERBBs?

Discover a study that investigated whether scheduled IV acetaminophen administration would offer longer-lasting relief for ...

Within cell membranes, ion channel receptors typically activate in response to electrical, chemical or other specific stimuli ...

Silent synapses are dormant neural connections that hold untapped brain potential. Discover how ketamine, exercise, and other ...

In addition to regulation of subcellular location, ERBB receptors are also regulated in ways that affect their signaling activity. Ultimately, the maturation, dimerization, activation, time of ...

PARP7 is a mono-ADP-ribosyl transferase (mono-ART) which has recently gained attention due to its emerging role as a negative ...

Hotter temperatures may render natural insect repellents less effective against mosquitoes, according to a new study.

Now, investigators at the Jacobs School of Medicine and Biomedical Sciences at the University at Buffalo have uncovered how heat causes a critical receptor protein within cells to unfold and relay ...