Mitochondria produce some of the proteins they need themselves—with the help of special protein factories called mitoribosomes, which consist of RNA and proteins. Researchers in Göttingen have ...

Dr. Ma's team found that chemical modification of RNA (called RNA methylation) regulates mitochondrial function. Mitochondria ...

Similarly, a homoplasmic mutation in a mitochondrial genome-encoded ribosomal RNA, called RNR1, causes postlingual deafness (deafness that occurs after three years of age, when a child has already ...

Blum, B., Bakalara, N. & Simpson, L. A model for RNA editing in kinetoplastid mitochondria: RNA molecules transcribed from maxicircle DNA provide the edited information. Cell 60, 189–198 (1990).

We have elected to study this process in the slime mold Physarum polycephalum (Pp), which carries out the widest range of RNA editing events yet described. These changes to mitochondrial RNAs involve ...

Selective reduction of OPA1 or MFN1 significantly rescued mitochondrial abnormalities, survival, and locomotor activity, whereas reduction of MFN2 had no effect. RNA sequencing of the pons/medulla ...