Researchers discovered that targeting S. pyogenes metabolism with a pyruvate dehydrogenase inhibitor reduces tissue damage ...

They synthesize ATP from pyruvate breakdown via simple fermentations that typically involve the production of molecular hydrogen as a major metabolic end product. These mitochondria are called ...

A new study reveals a novel approach to mitigating tissue damage caused by Streptococcus pyogenes, the flesh-eating bacterium responsible for severe infections such as necrotizing fasciitis. The ...

It tests an organism's ability to ferment the sugar glucose as well as its ability to convert the end product of glycolysis, pyruvic acid into gaseous byproducts ... is also used in these fermentation ...

This stage does not require oxygen. If oxygen is available to the cell then the pyruvate molecules can be further broken down in stage two to release more energy and produce a greater quantity of ATP.

A new study published in Nature Communications reveals a novel approach to mitigating tissue damage caused by Streptococcus ...