This concept originated from an obvious feature of the unifying mechanism (Fig ... important for vascular biology are eNOS and prostacyclin synthase (Fig. 12). Both are dramatically inhibited ...

They work by mimicking the effects of a natural hormone called prostacyclin. Their mechanism of action includes stopping platelets from forming clots in your blood vessels and causing vasodilation ...

When they injected recombinant CF6 into normal rats blood pressure increased, whereas a specific antibody to CF6 decreased systemic blood pressure concomitantly with an increase in plasma prostacyclin ...

Controversy about the mechanisms of potential cardiovascular ... effects of COX2-selective inhibitors might be caused by a prostacyclin and thromboxane imbalance, multiple opposing cardiovascular ...