A research team has established an innovative intracranial pre-olivary pretectal nucleus (OPN) optic tract injury model ...

Here, we explored how NMDARs signal in tLTD. We found that, regardless of frequency, L5 PC→PC tLTD relies on the non-ionotropic preNMDAR signaling pathway mediated by JNK2, which helps to resolve the ...

By influencing calcium homeostasis, local protein synthesis and the endoplasmic reticulum, a small protein called Rab10 emerges as a crucial cytoplasmic regulator of neuropeptide secretion.

Serafini and colleagues provide evidence that neuroligin acts as a trans-neuronal signal to induce presynaptic differentiation at neuron–neuron connections in vitro. To form a synaptic ...

An electrical impulse cannot directly cross the gap so a different mechanism has to be used. Between impulses the transmitter molecules are rapidly removed from the synaptic cleft to prevent ...