The nicotinic acetylcholine receptors (nAChRs ... promise for the rational design of drugs based on the atomic structure of their receptors. The figure illustrates the ion permeation pathway ...

This structure was identified first in the ... Her research focuses on understanding the roles of nicotinic acetylcholine receptors in the mammalian brain and the molecular and cellular events ...

Cytisine has a molecular structure similar to that of nicotine and varenicline, and it has similar pharmacological effects. Cytisine is a partial agonist of nicotinic acetylcholine receptors.

Additional studies in collaboration with Ibañez-Tallon showed that lynx-1 altered the function of nicotinic acetylcholine receptors. Acetylcholine is a neurotransmitter that helps to activate muscles ...