Interesting Engineering on MSN8d
Greenland sharks can live for 400 years without getting cancer, thanks to their DNA
The shark’s ability to maintain genomic stability over centuries may be attributed to a suite of enhanced DNA repair enzymes.
Hosted on MSN2mon
A potential pathway may guide new therapies for inflammatory bowel disease and other inflammatory diseases
Dr. Ma adds, "Our results show that BB1 prevented the TNF-α increase in intestinal tight junction permeability via a toll-like receptor (TLR)-2 signal transduction pathway inhibition of NF-kB p50 ...
Hosted on MSN1mon
Microglia reprogramming offers novel strategy to combat melanoma brain metastases
"We have identified a key signaling pathway, Rela/NF-kB, that, when blocked, reverses the protumoral function of microglia and activates an immune response against tumors," explains Sánchez ...
Nature4y
Structure and signaling of Toll-like receptors
The adaptors activate other relay proteins inside the cell, and this chain of protein-protein interactions creates a signal transduction pathway that ... factors (such as NF-kB and IRFs) that ...