Signal peptides, comprising the N-terminal 13–36 amino acids of secretory proteins, are necessary for the translocation across the first membrane on the secretory pathway and thus universally ...
1b). Figure 1: Identification of cSNP peptides via a modified database. In conclusion, the modified database described here allows efficient identification of N-terminal peptides and of cSNPs in ...
Hosted on MSN10mon
Therapeutic target identified to neutralize toxic forms of Parkinson's-associated proteinresearchers observed that PSMα3 acts by binding to one end of the alpha-synuclein (N-terminus) that regulates the oligomer-to-fibril conversion process. Upon binding, the peptide covers two small ...
Background Patients with transthyretin amyloid cardiomyopathy (ATTR-CM) often experience worsening cardiac disease (WCD) ...
Objective: To investigate if the exercise-induced immune response contributes to the exercise-induced increase in brain natriuretic peptide (BNP) in healthy athletes. This has previously been ...
Hosted on MSN1y
Study describes structure of antiviral drug bulevirtide bound to hepatitis B and D virus receptor protein NTCPPrevious studies have shown that the viral interaction with NTCP is mediated by the N-terminal myristoylated ... reported a cryo-EM structures of viral peptide bulevirtide-bound human NTCP at ...
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