The principal therapeutic action of morphine is analgesia. The precise mechanism of action is not known but the effects are thought to be mediated through opioid-specific receptors located in the CNS.

Although many dosing regimens for intravenous morphine have been studied, 0.10 mg/kg generally is recommended as an acceptable starting dose for treating patients with acute pain. Unfortunately ...

The risk to develop PTSD was significantly reduced (p<0.001) when morphine had been administered. This interaction remained significant after controlling for severity and mechanism of injuries ...

The drugs used in the present study were morphine sulfate (Temad Pharmaceutical, Tehran, Iran), agmatine sulfate, RX821002, UK 14 304 (Sigma, Germany), and yohimbine (Sigma, UK). The UK 14 304 ...