Mitochondria play a crucial role in acquiring pluripotency and determining cell fate. The mitochondrial unfolded protein ...

the number of mitochondrial genomes in each organelle—as part of a process called the mitochondrial unfolded protein response, or UPR mt. This process prompts the up-regulation of certain stress ...

The mitochondrial unfolded protein response (UPR mt) is a transcriptional program that is activated in cells experiencing mitochondrial stress and that helps to return to proteostasis and improve ...