A medical breakthrough could result in the first treatment for rare but serious diseases in which genetic defects disrupt ...

A medical breakthrough could result in the first treatment for rare but serious diseases in which genetic defects disrupt cellular energy production. Researchers have identified a molecule that helps ...

Ultimately, this is an alternative garbage disposal pathway used by cells to get rid of dysfunctional and damaged mitochondria when they cannot degrade the organelles in their own lysosomes. Why did ...

e. SecMRA helps refine the subtle mitochondrial cristae imaged by a STED microscope. f. SecMRA assists in long-term, low-toxicity imaging of mitochondria and ER by removing abundant noise and ...

Under ideal conditions, an optical microscope enables us to observe ... Simpson, L. A model for RNA editing in kinetoplastid mitochondria: RNA molecules transcribed from maxicircle DNA provide ...

[This study] exploits specific aspects of this technology.” The technique revolves around the mitochondrial fluorescent enzyme NADH, which can be observed via multiphoton microscopy. By focusing on ...

Figure 1. Inner membranes of live mitochondria under a STED microscope imaged using the MitoPB Yellow fluorescent marker molecule created by researchers at the Institute of Transformative Bio ...

Mitochondria produce some of the proteins they need themselves—with the help of special protein factories called mitoribosomes, which consist of RNA and proteins. Researchers in Göttingen have ...

Damage to the genetic material of mitochondria – the mitochondrial DNA or mtDNA for short – can lead to diseases such as Parkinson's, Alzheimer's, amyotrophic lateral sclerosis (ALS), cardiovascular ...