The first thing you should do here is to close all programs that are using the Excel file you are attempting to open. Please ensure the .xls file is not opened in other workbooks, add-ins, or apps.

Open Microsoft Excel.; Go to “File > Options > Trust Center.” Now, click on the Trust Center Settings button.; Select Protected View from the left side.; Uncheck all the options on the right ...

File-security limits can curtail your ability to open or save Microsoft Excel files. Getty Malware can exploit your computer and your private information, but only if it manages to install itself.

When attempting to open a document that has triggered the use of the Protected View feature, like an Excel document, a message would pop up saying, "Microsoft Excel cannot open or save any more ...

A fresh update for Microsoft Office 2008 delivers a fix for an Open XML compatibility issue that arose with Service Pack 2. {loadposition stephen08}Last month, Microsoft released Service Pack 2 ...