While metformin is widely used for glucose control and has a modest impact on weight, Ozempic is more effective for both glucose regulation and substantial weight loss, Dr. Glickman explains.

The increasing popularity of weight loss drugs like Wegovy, Ozempic, Mounjaro and metformin may have you wondering how all these options stack up. Are there benefits to one over the other?

Experts don’t recommend it solely for weight loss, due to insufficient data. Metformin primarily works by combatting insulin insensitivity, the main precursor of type 2 diabetes, and reducing ...

That said, experts don’t consider metformin a substitute for medications like Wegovy, which are FDA-approved for weight loss. “Sometimes people do lose weight on [metformin], and most people ...