How does the body regulate the activity of insulin-producing cells in order to react quickly to changing conditions? Researchers have investigated this question.

The hormone insulin plays a central role in the metabolism of many living organisms. When food is plentiful, insulin promotes ...

Background The study of endogenous insulin secretion may provide relevant insight into the comparison of the natural history of adult onset latent autoimmune diabetes (LADA) with types 1 and 2 ...

Reduced insulin secretion leads to elevated blood glucose levels and an increased risk of serious complications, such as cardiovascular disease and nerve damage. The exact mechanisms behind ...

In obesity and insulin resistance, increased secretion of proinflammatory cytokines ... has been associated with antiatherogenic mechanisms, whereas endothelium-derived vasoconstrictors, for ...

Zhen Huang, and Åke Sjöholm. "Ethanol acutely stimulates islet blood flow, amplifies insulin secretion, and induces hypoglycemia via NO and vagally mediated mechanisms" ...

20,21 A similar mechanism may account for the fact that ... and that simultaneously pancreatic insulin secretion was diminished by an amount equal to that elaborated by the tumor.

Impairment of insulin secretion and defects in insulin action ... production of polyol compounds from glucose are among the mechanisms thought to produce tissue damage from chronic hyperglycemia.