A total of 116 adolescents (45 girls and 71 boys) participated, and their mean age was 15.9 years. Systolic and diastolic blood pressure were measured using an aneroid sphygmomanometer.

In a double-blind, randomized trial with a 2-by-2 factorial design, we evaluated a mean arterial blood-pressure target of 63 mm Hg as compared with 77 mm Hg in comatose adults who had been ...