Computational model enhances protein kinase target prediction for therapies
Protein kinase research presents an opportunity to explore molecular targets in the body to treat diseases like cancer and ...
technologynetworks29d
Next-Generation Kinase Inhibitors: Overcoming Resistance and Enhancing Clinical Outcomes
Protein kinase inhibitors have revolutionized cancer treatment by targeting specific kinases involved in tumor growth and survival. As of 2024, over 80 small-molecule protein kinase inhibitors have ...
Janus Kinase (JAK) Inhibitor Pipeline Market Insights Report 2025: Comprehensive Review of 50+ Companies and Respective 55+ Drugs
The "Janus Kinase (JAK) Inhibitor - Pipeline Insight, 2025" drug pipelines has been added to ResearchAndMarkets.com's offering.The "Janus Kinase (JAK) Inhibitor- Pipeline Insight, 2025" report ...
ALZFORUM6d
Pretty in PINK1, Cryo-EM Reveals How Kinase Anchors to Mitochondria
This new cryo-EM structure represents a remarkable advance in our understanding of how human PINK1 is stabilized” said ...
Nature2mon
Recognizing and exploiting differences between RNAi and small-molecule inhibitors
Whereas small-molecule inhibition and the moderate overexpression of catalytic mutants simply reduces Aurora B kinase activity in the cell, RNAi disrupts the CPC, leading to a more global ...