Control mice were injected with aqueous vaccine using a 26.5-gauge needle. The subcutaneous injection was given in the scruff of the neck and the intramuscular injection was made in the upper thigh.

Notably, the intramuscular BMP-9 injection led to changes in the tissue resembling flare-ups, including abnormal cartilage and bone formation, as well as increased FAP accumulation, only in mice ...

What they have observed in rodents is verging on the miraculous: a team of scientists has given monthly injections of a simple antibody to mice that are almost 18 months old, an age equivalent to ...