Summary: Tocilizumab is a novel monoclonal antibody that competitively inhibits the binding of interleukin-6 (IL-6) to its receptor (IL ... modifying antirheumatic drugs. A large clinical trial ...

The drug is a fusion protein comprising the human interleukin (IL)-1 type 1 receptor ... drugs including Kinaret (anakinra), an IL-1 receptor antagonist approved to treat rheumatoid arthritis ...

BLA accepted for review Dupilumab (Regeneron and Sanofi) Interleukin-4 receptor alpha antagonist Treatment of ... Anti-programmed death receptor-1 (PD-1) therapy For the treatment of patients ...