Interestingly, glipizide was very similar to repaglinide with respect to the effects on the early phase. Moreover, glipizide reached significance against glibenclamide in both groups of subjects ...

Objective—Glucagon-like peptide 1 (GLP-1) exerts beneficial antidiabetic actions via effects on pancreatic β- and α-cells. Previous studies have focused on the improvements in β-cell function ...

Potential side effects include increased heart rates, hepatic glucose production, and loss of lean mass. Researchers have proposed combining GCGR agonists with insulinotropic agents, such as GLP-1 ...