These observations indicate that reduction of exogenous glucose uptake is associated with a marked reversible inhibition of insulin release in infants undergoing deep hypothermic cardiovascular ...

A combination of an SGLT-2 inhibitor drug and a moderately calorie-restrictive diet leads to higher rates of type 2 diabetes ...

pH levels and insulin work together to inhibit the buildup of protein clumps that contribute to this disease. The work, which points toward promising avenues for innovative treatments, was ...

Use of a sodium-glucose cotransporter 2, or SGLT2, inhibitor combined with calorie restriction resulted in greater rates of type 2 diabetes remission compared with calorie restriction alone, according ...

Reciprocally, iron influences insulin action. Iron interferes with insulin inhibition of glucose production by the liver. Hepatic extraction and metabolism of insulin is reduced with increasing ...

Tyrosine-protein phosphatase non-receptor type 1 (PTP1B) acts as a negative regulator of the insulin signaling pathway by dephosphorylating both the insulin receptor (IR) and the insulin receptor ...

while insulin and free fatty acids inhibit its release. Like glucagon, multiple factors similarly regulate insulin secretion such as amino acids, neurotransmitters and various hormones.

Dipeptidyl peptidase-IV inhibitors Inhibit peptide hormone metabolism ... on a meglitinide alone or metformin alone. Repaglinide, an insulin secretagog, and metformin, an insulin sensitizer ...