It can become overactive in cancer, driving uncontrolled cell growth, so the researchers designed a peptide inhibitor that binds to one half of cJun, stopping it from forming pairs and attaching ...
A natural antibacterial molecule shows clinical promise. Its unusual binding site is on an excellent target: ...
More information: Shun Nakamura et al, Structure-guided engineering of a mutation-tolerant inhibitor peptide against variable SARS-CoV-2 spikes, Proceedings of the National Academy of Sciences (2025).
This data confirms the model for lasso peptide folding that the researchers ... to efficiently produce a potent inhibitor of ...
has developed COVID-19 eliminative Short Peptide Inhibiting ACE2 binding (CeSPIACE), a mutation-tolerant spike protein inhibitor that remains effective against SARS-CoV-2 variants, including ...
"Since the tagged peptide was also receptor-targeted ... We found a dose-dependent inhibitory effect in a melanoma-bearing mouse model, confirming the effectiveness of our approach." ...
agonist KROS101 in melanoma and glioblastoma as well as its peptide inhibitor for macrophages KROS 401 in glioma animal models. In the presentation, titled “KROS 101: A Next Generation GITR ...
has developed COVID-19 eliminative Short Peptide Inhibiting ACE2 binding (CeSPIACE), a mutation-tolerant spike protein inhibitor that remains effective against SARS-CoV-2 variants, including ...
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