"Since the tagged peptide was also receptor-targeted ... We found a dose-dependent inhibitory effect in a melanoma-bearing mouse model, confirming the effectiveness of our approach." ...
Of the tau aggregation inhibitors and antibodies that they have generated ... We also assessed the effects of the peptide-MNPs on an AD mouse model and observed that the complex transversed the BBB ...
agonist KROS101 in melanoma and glioblastoma as well as its peptide inhibitor for macrophages KROS 401 in glioma animal models. In the presentation, titled “KROS 101: A Next Generation GITR ...
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Peptide screening reveals irreversible inhibitors for cancer's 'undruggable' cJun proteinIt can become overactive in cancer, driving uncontrolled cell growth, so the researchers designed a peptide inhibitor that binds to one half of cJun, stopping it from forming pairs and attaching to ...
suggest the drug may be superior to BMS’s TYK2 inhibitor deucravactitinib. Johnson & Johnson is now enrolling patients into the ICONIC-ASCEND phase III study to test the peptide against its best ...
has developed COVID-19 eliminative Short Peptide Inhibiting ACE2 binding (CeSPIACE), a mutation-tolerant spike protein inhibitor that remains effective against SARS-CoV-2 variants, including ...
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