For a simple linear regression model, ... If any assumption such as linearity, independence of errors, or homoscedasticity are violated, RSS may lead to biased estimates and incorrect inferences.

The attenuation factors estimated in a linear regression calibration model were 0.368 (0.228, 0.508) for nitrogen and 0.500 (0.361, 0.639) for potassium intakes; only the former was different from ...