For the first time, scientists have identified promising drug candidates that bind irreversibly with a notoriously ...

T cells constantly survey the body for signs of infection or malignancy through the recognition of fragments of antigens (peptides) complexed to molecules of the major histocompatibility complex.

Cyclic peptides, which combine characteristics of ... reversed the expression of GW4064-induced FXR target gene small heterodimer partner (Shp) in an FXR-dependent manner without significantly ...

Interestingly, when ErbB2 is overexpressed, heterodimers form preferentially. Unlike homodimers, which are either inactive (ErbB3 homodimers) or signal only weakly, ErbB2-containing heterodimers ...