Inhibition of NTE activity has been linked to neurological disorders such as organophosphate-induced delayed neuropathy, ...

Today, the company announced the submission of an Investigational New Drug (IND) application to the U.S. Food and Drug Administration (FDA) for its novel adeno-associated virus (AAV) gene therapy ...

One finisher, Andrew Patterson, thought he would not walk again after he was diagnosed in 2013 with hereditary spastic paraplegia, a disorder that causes weakness and stiffness in the leg muscles.

In particular we are investigating the involvement of axonal transport in diseases including motor neurone disease (MND) and hereditary spastic paraplegia (HSP). In addition we are developing and ...

Our research can shed light on the connection between the endoplasmic reticulum and many diseases, such as Alzheimer's disease and Hereditary spastic paraplegia.