If iPS cell lines could be derived from donors' somatic cells with an efficiency and safety profile that was comparable to ES cell lines, an opportunity exists to establish more efficient HLA ...

"We needed to make a new type of cell, because we were trying to target specific antigens called peptide-HLA (human leukocyte ... that are displayed on the cell surface by peptide-holding proteins ...

Over the past several years, significant advances in HLA antibody detection have occurred. Solid-phase, multiplex testing platforms have replaced traditional cell-based assays, and have provided ...

Their research, published in the journal Cell Systems on March ... of AI and machine learning, the HLA Inception tool analyzes electrostatic signatures on the surface of proteins to classify ...