Glipizide/metformin HCl ... Second-line: (previously treated with sulfonylurea or metformin only): 2.5mg/500mg or 5mg/500mg twice daily (AM & PM) (initial dose should not exceed previous daily ...

The longer-acting agents (e.g. chlorpropamide, glyburide [glibenclamide], and sustained-release glipizide) are more likely to cause hypoglycemia than glipizide, glimepiride, and gliclazide.

Data Synthesis: Studies of glyburide and glipizide have found little or no ... Glyburide has been used for the treatment of gestational diabetes, and metformin has been used in women with PCOS ...