Spatially resolved gene expression can provide a powerful complement to traditional histopathology methods, enabling a greater understanding of cellular heterogeneity and organization within the ...

These efforts identified functionally significant gene expression changes in human radial glia (Nature, 2014), interneurons (Cerebral Cortex, 2018), and astrocytes (Nature Neuroscience, 2018 ...

Synapses are junctions via which neurons communicate with each other or with other types of cells. Synapses are formed ...

This study reveals the step-wise establishment of nuclear speckle-associated domains (SPADs) during mouse embryogenesis. Using optimized CUT&Tag, researchers found paternal SPADs dominate pre-ZGA ...

Spatially resolved gene expression can provide a powerful complement to traditional histopathology methods, ... Resolving Brain Architecture With Comprehensive Spatial Gene Expression. App Note / Case ...

"The genetic changes that gave rise to the modern human brain were the catalyst for life as we know it," Dr. Oldham reflects in the interview. This fundamental question drove him to pursue a PhD ...

Spatially resolved gene expression can provide a powerful complement to traditional histopathology methods, enabling a greater understanding of cellular heterogeneity and organization within the ...