About 65% of melanoma patients do not respond to immunotherapy. New work by the team of Prof. Max Mazzone (VIB-KU Leuven ...

When there is enough product at the end of a reaction pathway (red macromolecule), it can inhibit its own synthesis by interacting with enzymes in the synthesis pathway (red arrow). Cells ...

Moreover, h15-LOX-2 and other LOX enzymes may be involved in ferroptosis, a form of iron-dependent cell death associated with lipid peroxidation. In this case, inhibition of the enzyme may be ...

Genes for some of the enzymes in a cell are expressed so that the enzymes are always present. Influencing their activity can control their rates of reaction. Different chemicals can influence ...

Moreover, h15-LOX-2 and other LOX enzymes may be involved in ferroptosis, a form of iron-dependent cell death associated with lipid peroxidation. In this case, inhibition of the enzyme may be ...