If you receive Microsoft Excel cannot access the file, There are several possible reasons error message you can use the following suggestions to resolve the issue.

If you receive Cannot open the Clipboard error message when clicking or copy-pasting cells in Excel, take a look at your addins first and then use these fixes.

Microsoft on Thursday released a pair of updates to fix a problem with Open XL documents: Microsoft Office 2008 for Mac 12.2.1 Update and Microsoft Office Open XML File Format Converter 1.1.1.