New toolbox aids in characterizing internal ribosomal entry sites in cells
Only recently has the ribosome—one of the oldest molecular machines in evolutionary terms—been recognized as an active ...
Nature4y
Translation: DNA to mRNA to Protein
What individual substeps are a part of this process? And does translation differ between prokaryotes and eukaryotes? The answers to questions such as these reveal a great deal about the essential ...
Hosted on MSN3mon
Protein Synthesis in Prokaryotes vs. Eukaryotes: What’s the Difference?
In eukaryotic cells like human cells, transcription occurs in the nucleus, and the resulting mRNA is then transported to the cytoplasm for translation. Additionally, eukaryotic mRNA often ...
News Medical on MSN10d
Starting points for the control of protein synthesis
The research field of "cellular IRESes" lay dormant for decades, as there was no uniform standard of reliable methods for the clear characterization of these starting points for the ribosome-mediated ...
BioWorld6d
Canadian research institutions patent new GCN2 inhibitors
Investigators from the Ontario Institute for Cancer Research and the University Health Network have synthesized triazolopyridopyrimidine and dihydroimidazopyridopyrimidine derivatives acting as ...