Force From Filament, the Tether Model of Mechanosensitive Ion Channels In the model of the force-from-filament, the cytoskeleton and/or ECM proteins connect to MS ion channels, directly or indirectly ...

Angiopoietin-like 4 (ANGPTL4) is a secreted protein that belongs to the angiopoietin family and is involved in angiogenesis and metabolism regulation. We previously reported the induction of angptl4 ...

News & Views Published: November 1999 Unravelling the extracellular matrix Amy Shaub Nature Cell Biology 1, E173–E174 (1999) Cite this article ...

In this Abstract, we will present genetic validation evidence supporting the efficacy of pharmaceutical modulation of the cytoskeleton and the associated ECM that supports its cellular architecture to ...

Extracellular matrix (ECM) plays a critical role in regulating cell behaviors such as proliferation, spreading, migration and differentiation. Here we investigate ECM micro-patterns as a factor of ...

These data suggest that ECM–integrin–cytoskeleton focal adhesion linkages could be important for gating some MS channels (Matthews et al., 2006; Matthews et al., 2007; Martinac, 2014; Ellefsen et al., ...