One of the major constituents of the cell-adhesion complex ... of lobular breast tumors, and E-cadherin germline mutations in cases of familial diffuse gastric cancer argue strongly in favor ...

E-cadherin is a transmembrane glycoprotein involved in epithelial cell adhesion. In cancer, downregulation of this protein enhances tumor cell dissociation, thereby increasing the risk of ...

Lurie Comprehensive Cancer Center of Northwestern University ... early steps of interactions between the cytoskeleton and E-cadherin, the cellular "glue" protein. They found that before cells make ...

The junction protein E-cadherin plays a significant role in the intercellular force transmission in epithelia. It contributes to cells attaching themselves to each other (cell adhesions ...

The junction protein E-cadherin plays a significant ... acute inflammation and even cancer." More information: Andreas Schoenit et al, Force transmission is a master regulator of mechanical cell ...

Time-lapse video of competition within patient-derived metaplastic cancer cells ... caused by variations in E-cadherin adhesion strength, shaping the dynamics of cell competition.

Northwestern Medicine investigators have uncovered new insights into how intercellular "glue" functions to enable interactions between cells ... the cytoskeleton and E-cadherin, the cellular ...