Acquisition of invasive and metastatic capabilities is frequently associated with loss of cell–cell adhesion. One of the major constituents of the cell-adhesion complex in epithelial cells is E ...

E-cadherin is a transmembrane glycoprotein involved in epithelial cell adhesion. In cancer, downregulation of this protein enhances tumor cell dissociation, thereby increasing the risk of ...

Northwestern Medicine investigators have uncovered new insights into how intercellular "glue" functions to enable interactions between cells, as detailed in a study published in Nature Communications.

The junction protein E-cadherin plays a significant ... acute inflammation and even cancer." More information: Andreas Schoenit et al, Force transmission is a master regulator of mechanical cell ...