A component critical to the model's learning process is a mechanism that emulates the human brain's dopamine delivery system, Soni said. When the model was doing a better job of recalling the ...

More information: Josep Carbonell-Roig et al, Dysregulated acetylcholine-mediated dopamine neurotransmission in the eIF4E Tg mouse model of autism spectrum disorders, Cell Reports (2024).

Most people are familiar with Pavlovian conditioning, in which a reward-anticipatory behavior follows a reward-predicting ...

Using a mouse model, the researchers found that treatment with dopamine could alleviate physical symptoms in the brain as well as improve memory. Published in the journal Science Signaling on ...

Luckily, monogamous prairie voles have turned out to be a good model for studying the formation of pair bonds. University of Colorado Boulder neuroscientist Zoe Donaldson found that dopamine may play ...

In this model, impulsivity provides strong parallels with addiction—with links to a specific behavior (cocaine self-administration) and to changes in signaling of a neurotransmitter (dopamine).

Dopamine is an inotropic agent that has vasodilatory effects at low doses. It is a common belief that low-dose dopamine may be helpful in the prevention and treatment of acute renal failure and is ...

Patients' own stem cells to replace damaged dopamine cells in Parkinson's disease, offering new hope.

Phasic dopamine cell body activity and release in the nucleus accumbens differentially respond to the taste of sucrose in correlation with its hedonic valuation.

A recently launched Phase 1 clinical trial at Mass General Brigham is examining the safety and feasibility of a groundbreaking treatment approach for Parkinson's disease in which a patient's stem ...