A research team led by Dr. Martin Mollenhauer from the Heart Center at University Hospital Cologne has investigated the link ...

Disappointingly, a third drug also tested in the study failed to show additive efficacy in RA when combined with tofacitinib ...

Small-molecule enzyme-inhibitors often display insufficient affinity and selectivity for their targets causing unwanted side effects when used as drugs. Molecularly imprinted polymers prepared ...

The mechanism of enzyme catalysis is similar in principle to other types of chemical catalysis, for instance by involving a combination of several different ... some Hsp90 inhibitors are ...

The Michaelis-Menten equation helps researchers understand the behavior of enzymes under different conditions and can be used to determine important kinetic parameters, such as V max and K M. As our ...

New research offers unprecedented insight into how an enigmatic enzyme, known as CDK7 ... representing 27 different tissue types. This points, for the first time, to a universal mechanism by ...