Indeed, for NF-κB and NFAT, the DNA-binding domain is comprised of two Ig-fold regions; the N-terminal Ig-motif is responsible for sequence-specific DNA binding and the linker region that ...

Within the NTase domain is an adenylate binding pocket composed of the six peptide motifs (I, Ia, III, IIIa, IV, and V) that define the covalent nucleotidyltransferase enzyme superfamily that includes ...

They explored combinations of various polymerases and DNA binding domains, focusing on structural motifs from nature. They were particularly drawn to features of T7 DNA polymerase—derived from the T7 ...

Fragments with CENPC/CENPC-k motifs and DNA-binding regions can ... in plants depends on their centromere-targeting domain and DNA-binding regions, Nucleic Acids Research (2024).

How did eukaryotic organisms become so much more complex than prokaryotic ones, without a whole lot more genes? The answer lies in transcription factors. Experiments have shown that TFs can bind ...