This study reveals how SV40 helicase unwinds DNA, highlighting ATP hydrolysis's role in translocation and offering insights ...

For the first time, researchers have filmed in real time the disassembly of DNA at the atomic scale. This strand separation ...

A University of Iowa-led study has revealed the unexpected structure adopted by the DNA repair protein RAD52 as it binds and ...

Scientists have provided the most detailed account yet of the earliest stages of DNA replication, an essential process for ...

Gepotidacin is an oral, first-in-class triazaacenaphthylene antibiotic that inhibits bacterial DNA replication by blocking 2 different type II topoisomerase enzymes.

Researchers harness the power of the world’s most advanced supercomputers to simulate the inner workings of cellular ...

Scientists have captured the first detailed 'molecular movie' showing DNA being unzipped at the atomic level -- revealing how cells begin the crucial process of copying their genetic material.

Upon binding, helicases melt the DNA, breaking the chemicals bonds holding the double helix together. They then pull the two strands apart, allowing other enzymes to complete the replication.

MSK researchers shed new light on G-quadruplexes, a type of secondary DNA structure that has attracted attention as a potential therapeutic target in cancer.

Scientists at the University of Leicester have captured the first detailed "molecular movie" showing DNA being unzipped at the atomic level – revealing how cells begin the crucial process of copying ...

The effect of saccharin on the microbiome has received much attention, but its impact on pathogenic bacterial species is less ...

The enzymes that handle DNA molecules are often called "polymerases," but the -ase suffix denotes an enzyme. When not undergoing replication, DNA molecules float freely within the cytoplasm of a cell.