We have developed a non-radioactive flow-cytometry assay to monitor and quantify the target-cell killing activities mediated by cytotoxic T lymphocytes (CTLs). This flow-cytometry CTL (FCC ...
Triple-negative breast cancer, an aggressive type of breast cancer, accounts for 10% of all breast cancer cases in the United ...
CD8-positive T cells are a critical subpopulation of MHC class I-restricted T cell and are mediators of adaptive immunity. They include cytotoxic T cells, which are important for killing cancerous ...
A groundbreaking study published in Research (2025, DOI: 10.34133/research.0545) has elucidated the molecular mechanisms by which protein phosphatase 2A (PP2A) regulates CD8+ T cell-mediated immune ...
Then, the team discovered that mice lacking IL-10 had more—and more lethal—tumors, while mice overexpressing IL-10 had no tumors. The researchers found that IL-10 induces the production of additional ...
Image Credit: Promega Corporation Multiplex with other cell viability or cytotoxicity assays Multiplexing the CellTiter-Glo® 2.0 cell viability assay with other assays can decrease labor and ...
Results that may be inaccessible to you are currently showing.
Hide inaccessible results
Feedback