Chromosomal translocations occur in leukemias, lymphomas, sarcomas and some epithelial tumors and some generate unique fusion proteins. These translocation products may provide tumor-specific ...

Translocations generate novel chromosomes, but are often linked to disorders like infertility and cancer. How do these new chromosomes generate problems, and how are they detected? Translocations ...

A century after Down syndrome was first described, scientists discovered that the root cause of this disorder is a condition called trisomy 21. What strides in research have been made since then?

Professor Terry Rabbitts’ research is focussed on new strategies using intracellular antibodies and derivates for therapy aimed at hard-to-drug chromosomal translocation gene products. Our research is ...

This genetic variation is known as translocation Down syndrome. While Trisomy 21 causes down syndrome, there are three types of Trisomy chromosomal changes that occurs: Complete Trisomy 21 ...

All array platforms will detect copy number variations including deletions, duplications, unbalanced translocations, some marker chromosomes and aneuploidy. SNP arrays have the added advantage of ...

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